It’s clear just from the title of this new mini-series that Marvel isn’t trying to hide the fact that this is a shameless cash-grab of a sequel. Points for honesty, I suppose. But that does nothing to change the fact that this is a story we’ve seen before, and there’s little in this first issue that suggests the formula needed another rehash.
Deadpool Kills the Marvel Universe Again isn’t a direct sequel to the original mini-series, even though it features the same creative team (writer Cullen Bunn and artist Dalibor Talajic). Instead, it’s more an alternate take on the same basic concept. This is a different branch of the Marvel multiverse, one modeled pretty closely on the All-New, All-Different Marvel status quo. But the end result is mostly the same, with Deadpool compelled to slaughter every Marvel hero he can find.